CJC-1295 + Ipamorelin
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Retatrutide 10 mg
Still in clinical trials.
$190
High-purity Retatrutide, a weight-loss peptide still in clinical trials. For adults with obesity or overweight, the people its trials study. It has not finished its trials, so less is known about it than about Semaglutide or Tirzepatide.
- 99% purity or higher
- Sterile, tested by PCR
- Non-pyrogenic, tested by LAL
- Tested in the USA
- Free shipping in Mexico
- Pay by SPEI bank transfer
Your dose, on the dial.
The dial counts in units of 0.01 mL: 10 units is 0.10 mL, and 100 units, the most one press gives, is 1 mL. How much peptide a unit holds depends on the pen’s strength, so the same number of units gives a different dose on each pen. Enter the dose your doctor gave you to see how many units to set.
Enter your dose to see the number to set.
About Retatrutide
What Retatrutide is
Retatrutide is a peptide built to act like three hormones that help control appetite and how your body uses energy. Tirzepatide acts like two of them.
Retatrutide is still in clinical trials, and no country has approved it as a medicine. Its trials give it once a week, by injection under the skin, starting low and raising the dose step by step.
What Retatrutide is studied for
- Weight: Studied in large trials of adults with obesity or overweight, lasting more than a year and a half.
- Type 2 diabetes: Studied in adults with type 2 diabetes.
- Knee pain: Studied in adults with obesity and arthritis of the knee.
- Liver fat: Studied in a smaller, earlier trial.
What the research shows.
Still in clinical trials.
Retatrutide’s trials are the last stage of testing before a medicine can be approved, and no country has approved it yet. They gave it once a week by injection under the skin, starting low and raising the dose step by step. Each study used its own supply, dose and schedule, so its results describe that study rather than promise what this pen will do.
Weight
Large trials, Under the skin
In an 80-week trial of 2,339 adults with obesity or overweight, people on the highest dose lost 25.0% of their body weight on average, against 3.9% on a placebo. Those who kept taking it throughout lost 28.3%.
Type 2 diabetes
Large trials, Under the skin
In adults with type 2 diabetes, body weight fell by 20.8% on retatrutide, against 4.0% on a placebo.
Knee pain
Large trials, Under the skin
In adults with obesity and arthritis of the knee, knee pain fell by 75.8% on retatrutide, against 40.3% on a placebo.
Liver fat
Small studies, Under the skin
In a smaller, earlier trial, the fat in people’s livers fell by up to 82%.
How every lot is tested
Every lot of Retatrutide goes through three tests before it is sold.
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Every lot is 99% pure or more, and your pen’s exact purity is printed on its tube.
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Every lot we sell has passed the sterility test: no bacteria or other microbes were detected.
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Every lot we sell has passed the test for endotoxins, traces of bacteria that can cause fever after an injection.
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An independent laboratory in the USA runs every test.
Side effects and cautions
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At the highest dose, 11.3% of people stopped taking it because of side effects, against 4.9% on a placebo. Urinary infections were more common, and in an earlier trial heart rate rose.
Sources: Pharmacy Times, 2026 (opens in a new tab); Jastreboff, NEJM 2023 (opens in a new tab)
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In the knee trial, about one person in five on retatrutide felt unusual sensations on the skin, against fewer than one in a hundred on a placebo.
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Retatrutide acts like three hormones, where tirzepatide acts like two. Whether that makes retatrutide work better is not yet known, because the trial comparing them has not reported.
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Some of the weight lost is muscle and other lean tissue rather than fat: about 31% on average across trials of medicines of this kind.
Allergy warning
Don’t use Retatrutide if you have ever had an allergic reaction to it or to anything else in the pen. Get help straight away if you have swelling of the face, lips or throat, trouble breathing, or a rash that spreads after an injection.
Pregnancy and breastfeeding
Don’t use Retatrutide if you are pregnant or breastfeeding, or trying to become pregnant. Its trials did not include pregnant women.
Medicines and health conditions
If you take any medicine or have a health condition, talk with your doctor before using Retatrutide, and tell them you use it.
Clinical trials
Retatrutide is still in clinical trials. Its trials are the last stage of testing before a medicine can be approved, and what is known about its side effects comes from them alone.
Thyroid
In rats and mice, medicines of this kind caused tumors of the thyroid. Whether they do in people is not known. Don’t use this pen if you or anyone in your family has had medullary thyroid cancer, or if you have multiple endocrine neoplasia type 2 (MEN 2). Tell your doctor about a lump or swelling in your neck, trouble swallowing or a hoarse voice that won’t go away.
Stomach, pancreas and gallbladder
Stop and see a doctor straight away if you have severe pain in your stomach that won’t go away, with or without vomiting: it can be a sign of an inflamed pancreas. Medicines of this kind have also been linked to gallstones. Vomiting and diarrhea can dry you out, which can strain the kidneys, so drink enough fluids.
Low blood sugar
If you take insulin or another medicine that lowers blood sugar, your blood sugar can fall too low. Your doctor may need to change those medicines.
Before surgery
Tell your doctor or anesthetist that you use this pen before any surgery or procedure with anesthesia or sedation. Medicines of this kind slow the emptying of the stomach.
Heart rate
In an earlier trial, heart rate rose on Retatrutide. Talk with your doctor first if you have a heart condition.
Age
For adults 18 and over.
Frequent questions
Is Retatrutide approved?
No. Retatrutide is still in clinical trials, and no country has approved it as a medicine yet. Its trials are the last stage of testing before approval.
Is Retatrutide right for me?
Retatrutide has been studied in adults with obesity or overweight, some with type 2 diabetes or arthritis of the knee. Because it is still in trials, less is known about it than about Semaglutide or Tirzepatide. Talk with your doctor before you start.
How is Retatrutide different from Tirzepatide?
Retatrutide acts like three hormones, where Tirzepatide acts like two. Whether that makes Retatrutide work better is not yet known, because the trial comparing them has not reported.
How often is Retatrutide taken?
In its trials, Retatrutide was taken once a week by injection under the skin, starting on a low dose and raising it step by step. Follow the schedule your doctor sets.
What side effects can Retatrutide cause?
As with medicines of its kind, most side effects are in the stomach and gut, such as nausea, diarrhea and vomiting. At the highest dose, 11.3% of people stopped because of side effects, against 4.9% on a placebo. Some felt unusual sensations on the skin, and urinary infections were more common.
What testing does Pure99 complete for Retatrutide?
Every lot of Retatrutide is tested by an independent laboratory in the USA before it is sold. The laboratory measures its purity by HPLC, tests it for bacteria and other microbes by PCR, and measures its endotoxins by LAL. Endotoxins are the toxins bacteria leave behind even in a sterile solution, and they can cause fever and aches after an injection.
How much Retatrutide should I take?
Take Retatrutide only as your doctor directs: Pure99 doesn’t recommend a dose. The pen’s dial counts in units of 0.01 mL, from 1 to 100 a press, and the same number of units gives a different dose on each pen and each strength. The dose guide on this page turns your dose into the number of units to set.
How many doses are in one Retatrutide pen?
Every pen holds 3 mL, which is 300 units on the dial. How many doses that makes depends on your dose: the dose guide on this page shows how many doses of your size a pen holds.
