Popular
BPC-157
Injury Healing Gut & Tissue Repair
Come back from a tendon injury.
$140
High-purity TB-500, the whole thymosin beta-4 molecule, for muscles and tendons. For people getting back to training after an injury.
The dial counts in units of 0.01 mL: 10 units is 0.10 mL, and 100 units, the most one press gives, is 1 mL. How much peptide a unit holds depends on the pen’s strength, so the same number of units gives a different dose on each pen. Enter the dose your doctor gave you to see how many units to set.
Enter your dose to see the number to set.
This pen holds the whole thymosin beta-4 molecule, a protein found in almost every cell in the body, which helps cells move and form new blood vessels. Elsewhere, the name TB-500 often means a small fragment of it.
Its trials in people mostly used eye drops, a wound gel or drips into a vein. None studied muscles or tendons.
This pen holds the whole thymosin beta-4 molecule, a protein found in almost every cell in the body. Elsewhere, the name TB-500 often means a small fragment of it. Its trials in people mostly used eye drops, a wound gel or drips into a vein, and none studied muscles or tendons. Each study used its own supply, dose and schedule, so its results describe that study rather than promise what this pen will do.
Small studies, Gel on the skin
In a trial of 73 people with leg ulcers, the researchers concluded only that a thymosin beta-4 gel may help wounds heal faster.
Source: Guarnera, Ann N Y Acad Sci 2010 (opens in a new tab)
Small studies, Eye drops
In a small trial for damaged corneas, 6 of 10 eyes healed on thymosin beta-4 drops, against 1 of 8 on a placebo, a difference too small to be sure of.
Animal studies, Rats and mice
In rats, tendons and ligaments healed better. In mice, it drew the cells that repair muscle toward an injury.
Sources: Xu, Regul Pept 2013 (opens in a new tab); Hara, Vitam Horm 2011 (opens in a new tab)
Every lot of TB-500 goes through three tests before it is sold.
Every lot is 99% pure or more, and your pen’s exact purity is printed on its tube.
Every lot we sell has passed the sterility test: no bacteria or other microbes were detected.
Every lot we sell has passed the test for endotoxins, traces of bacteria that can cause fever after an injection.
An independent laboratory in the USA runs every test.
No published study has given thymosin beta-4 to people by injection under the skin. In a safety study, daily drips into a vein of up to 1,260 mg for 14 days were well tolerated.
In mice, melanoma cells made to produce extra thymosin beta-4 grew larger tumors and spread to the lungs four times as often.
The World Anti-Doping Agency bans TB-500 (thymosin beta-4) in sport at all times, so an athlete who is tested for doping and uses this pen risks a violation.
Source: World Anti-Doping Agency, Prohibited List 2026 (opens in a new tab)
Don’t use TB-500 if you have ever had an allergic reaction to it or to anything else in the pen. Get help straight away if you have swelling of the face, lips or throat, trouble breathing, or a rash that spreads after an injection.
TB-500 has not been studied in pregnancy or breastfeeding. If you are pregnant, trying to become pregnant or breastfeeding, talk with your doctor before using it.
If you take any medicine or have a health condition, talk with your doctor before using TB-500, and tell them you use it.
In lab studies, BPC-157 helps new blood vessels grow, and in mice, extra thymosin beta-4 made melanoma tumors grow larger and spread. Talk with your doctor first if you have or have had cancer.
For adults 18 and over.
TB-500 is for people getting back to training after an injury. Its studies of muscles and tendons were in animals, and its trials in people used eye drops and a wound gel, so no one can yet say what an injection does in people. Talk with your doctor before you start.
This pen holds the whole thymosin beta-4 molecule. Some products sold as TB-500 hold a small fragment of it instead.
No published study has given thymosin beta-4 to people by injection under the skin, so how it acts that way in people, and its side effects, are not known. In a safety study, daily drips of it into a vein for 14 days were well tolerated.
Every lot of TB-500 is tested by an independent laboratory in the USA before it is sold. The laboratory measures its purity by HPLC, tests it for bacteria and other microbes by PCR, and measures its endotoxins by LAL. Endotoxins are the toxins bacteria leave behind even in a sterile solution, and they can cause fever and aches after an injection.
Take TB-500 only as your doctor directs: Pure99 doesn’t recommend a dose. The pen’s dial counts in units of 0.01 mL, from 1 to 100 a press, and the same number of units gives a different dose on each pen. The dose guide on this page turns your dose into the number of units to set.
Every pen holds 3 mL, which is 300 units on the dial. How many doses that makes depends on your dose: the dose guide on this page shows how many doses of your size a pen holds.
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Injury Healing Gut & Tissue Repair
Come back from a tendon injury.
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