NAD+
Cellular Energy Metabolism & Healthy Aging
For healthy aging.
$160
High-purity MOTS-c, the mitochondrial peptide, for metabolism and healthy aging. For adults interested in metabolism and healthy aging. Every result so far comes from mice.
The dial counts in units of 0.01 mL: 10 units is 0.10 mL, and 100 units, the most one press gives, is 1 mL. How much peptide a unit holds depends on the pen’s strength, so the same number of units gives a different dose on each pen. Enter the dose your doctor gave you to see how many units to set.
Enter your dose to see the number to set.
MOTS-c is a short peptide coded in the DNA of your mitochondria, the parts of each cell that make energy, rather than in the DNA of the cell’s nucleus.
Every result so far comes from mice. No published study has given MOTS-c to people, and a first trial, in adults with prediabetes, is now recruiting.
MOTS-c is a short peptide coded in the DNA of your mitochondria, the parts of each cell that make energy. Every result so far comes from mice, and no published study has given MOTS-c to people. Each study used its own supply, dose and schedule, so its results describe that study rather than promise what this pen will do.
Animal studies, Mice
Mice on a high-fat diet given daily injections of MOTS-c stayed about 20% lighter than mice without it.
Animal studies, Mice
After two weeks of injections, old mice ran about twice as far as untreated mice.
Animal studies, Mice
In the same study, treated mice did not live significantly longer than untreated mice.
Every lot of MOTS-c goes through three tests before it is sold.
Every lot is 99% pure or more, and your pen’s exact purity is printed on its tube.
Every lot we sell has passed the sterility test: no bacteria or other microbes were detected.
Every lot we sell has passed the test for endotoxins, traces of bacteria that can cause fever after an injection.
An independent laboratory in the USA runs every test.
In human blood, MOTS-c is quickly cut into pieces.
A trial in adults with prediabetes is now recruiting.
Source: ClinicalTrials.gov, NCT07505745 (opens in a new tab)
The World Anti-Doping Agency bans MOTS-c in sport at all times, so an athlete who is tested for doping and uses this pen risks a violation.
Source: World Anti-Doping Agency, Prohibited List 2026 (opens in a new tab)
Don’t use MOTS-c if you have ever had an allergic reaction to it or to anything else in the pen. Get help straight away if you have swelling of the face, lips or throat, trouble breathing, or a rash that spreads after an injection.
MOTS-c has not been studied in pregnancy or breastfeeding. If you are pregnant, trying to become pregnant or breastfeeding, talk with your doctor before using it.
If you take any medicine or have a health condition, talk with your doctor before using MOTS-c, and tell them you use it.
For adults 18 and over.
MOTS-c is for people interested in metabolism and healthy aging. Every result so far comes from mice, so no one can yet say what it does in people. Talk with your doctor before you start.
Not yet. No published study has given MOTS-c to people. A trial in adults with prediabetes is now recruiting.
No published study has given MOTS-c to people by injection under the skin, so how it acts that way in people, and its side effects, are not known. Tell your doctor about any reaction where you inject it, or anything else unusual.
Every lot of MOTS-c is tested by an independent laboratory in the USA before it is sold. The laboratory measures its purity by HPLC, tests it for bacteria and other microbes by PCR, and measures its endotoxins by LAL. Endotoxins are the toxins bacteria leave behind even in a sterile solution, and they can cause fever and aches after an injection.
Take MOTS-c only as your doctor directs: Pure99 doesn’t recommend a dose. The pen’s dial counts in units of 0.01 mL, from 1 to 100 a press, and the same number of units gives a different dose on each pen. The dose guide on this page turns your dose into the number of units to set.
Every pen holds 3 mL, which is 300 units on the dial. How many doses that makes depends on your dose: the dose guide on this page shows how many doses of your size a pen holds.
Cellular Energy Metabolism & Healthy Aging
For healthy aging.
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